The All of Us Research Program released new Curated Data Repositories (CDRs) for Registered and Controlled Tier Data. The CDRs for both tiers will now include participant data with a cutoff date of 1/1/2022. Major changes are listed below.

Overview of Registered Tier (RT) changes

• Participant number increased to over 366,000 with at least one type of associated Registered Tier data
• Refreshed Wearables and EHR data
• Updated to the newest version of the OMOP data model (OMOP v5.3.1)
• Added 3 new COVID-19 Minute Surveys
• Added a new Social Determinants of Health (SDOH) Survey

Overview of Controlled Tier (CT) changes

Along with the RT changes listed above, additional changes include: 

• Participant number increased to over 369,000 with at least one type of associated Controlled Tier data
• Updated variant call files (VCFs), Intensity Data files (IDATs), Hail MatrixTable, & PLINK BED file for 165,127 Array samples 
• Updated VCFs and Hail MT for 98,590k samples in WGS joint callsets
• Introduced CRAM files for WGS samples 
• Updated genomic data auxiliary, QC, and annotation files 

For detailed information regarding the CDR changes, please see the full release notes documents:

RT CDR Full Release Notes

CT CDR Full Release Notes