The All of Us Research Program has launched several research initiatives in response to the coronavirus disease 2019 (COVID-19) pandemic. These initiatives, detailed in a June 2020 press release from the program, are as follows:  

• Antibody testing: Blood samples from over 24,000 participants were assessed for coronavirus antibodies to help researchers understand the prevalence of coronavirus exposure among All of Us participants and its variability across population groups and geographic regions [see Althoff, K., Schlueter, D.J., Anton-Culver, H., Cherry, J., Denny, J., Thomsen, I., ... Schully, S. (2021). Antibodies to SARS-CoV-2 in All of Us Research Program participants, January 2 - March 18, 2020. Clinical Infectious Diseases, ciab519, https://doi.org/10.1093/cid/ciab519.
  
  
• COVID-19 Participant Experience (COPE) survey: Participants who have completed the Basics survey have been invited to complete COVID-19 specific surveys to help researchers understand the effects of the COVID-19 pandemic on participants’ physical and mental health. The survey also includes questions about COVID-19 symptoms, social distancing, and economic impacts.
  
  
• Electronic health records: Methods for standardizing electronic health record information specific to COVID-19 tests, diagnoses, symptoms, and treatments are being explored to help researchers look for patterns, learn more about COVID-19 symptoms and associated health problems, and explore the effects of different medicines and treatments.

Table 1: Anticipated Timelines & Availability of Data for All of Us COVID-19 Initiatives

COVID-19 Participant Experience (COPE) Survey Data Resources

The COPE survey was first circulated to participants for a one month period in May 2020. A second monthly survey was circulated in June, another in July (which remained open for completion through September), November, and December. Surveys underwent minor, iterative changes month-to-month. An outline of changes can be found here. All response data except COVID-19 test and diagnoses are available to researchers in the Registered Tier (see Table 2 below for exact concepts suppressed). As with all other All of Us surveys, these data are mapped to an All of Us specific PPI vocabulary and stored in the OMOP observation table. For additional information on using COPE Surveys in your research, please see our Featured Workspace on “How to Work with All of Us Survey Data” found here.

Table 2: Survey Question Fields Suppressed from the Registered Tier